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Somatic role of SYCE2: an insulator that dissociates HP1α from H3K9me3 and potentiates DNA repair

The synaptonemal complex is a proteinaceous structure essential for meiotic recombination, and its components have been assumed to play a role exclusively in the germ line. However, SYCE2, a component constituting the synaptonemal complex, is expressed at varying levels in somatic cells. Considering...

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Detalles Bibliográficos
Autores principales: Hosoya, Noriko, Ono, Masato, Miyagawa, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238414/
https://www.ncbi.nlm.nih.gov/pubmed/30456351
http://dx.doi.org/10.26508/lsa.201800021