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Transcriptional repression by FACT is linked to regulation of chromatin accessibility at the promoter of ES cells
The conserved and essential histone chaperone, facilitates chromatin transcription (FACT), reorganizes nucleosomes during DNA transcription, replication, and repair and ensures both efficient elongation of RNA Pol II and nucleosome integrity. In mammalian cells, FACT is a heterodimer, consisting of...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Life Science Alliance LLC
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238418/ https://www.ncbi.nlm.nih.gov/pubmed/30456357 http://dx.doi.org/10.26508/lsa.201800085 |