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Transcriptional repression by FACT is linked to regulation of chromatin accessibility at the promoter of ES cells

The conserved and essential histone chaperone, facilitates chromatin transcription (FACT), reorganizes nucleosomes during DNA transcription, replication, and repair and ensures both efficient elongation of RNA Pol II and nucleosome integrity. In mammalian cells, FACT is a heterodimer, consisting of...

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Detalles Bibliográficos
Autores principales: Mylonas, Constantine, Tessarz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238418/
https://www.ncbi.nlm.nih.gov/pubmed/30456357
http://dx.doi.org/10.26508/lsa.201800085