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Ribosomal stalling landscapes revealed by high-throughput inverse toeprinting of mRNA libraries

Although it is known that the amino acid sequence of a nascent polypeptide can impact its rate of translation, dedicated tools to systematically investigate this process are lacking. Here, we present high-throughput inverse toeprinting, a method to identify peptide-encoding transcripts that induce r...

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Detalles Bibliográficos
Autores principales: Seip, Britta, Sacheau, Guénaël, Dupuy, Denis, Innis, C Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238534/
https://www.ncbi.nlm.nih.gov/pubmed/30456383
http://dx.doi.org/10.26508/lsa.201800148