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Role of Cnot6l in maternal mRNA turnover

Removal of poly(A) tail is an important mechanism controlling eukaryotic mRNA turnover. The major eukaryotic deadenylase complex CCR4-NOT contains two deadenylase components, CCR4 and CAF1, for which mammalian CCR4 is encoded by Cnot6 or Cnot6l paralogs. We show that Cnot6l apparently supplies the m...

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Detalles Bibliográficos
Autores principales: Horvat, Filip, Fulka, Helena, Jankele, Radek, Malik, Radek, Jun, Ma, Solcova, Katerina, Sedlacek, Radislav, Vlahovicek, Kristian, Schultz, Richard M, Svoboda, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238536/
https://www.ncbi.nlm.nih.gov/pubmed/30456367
http://dx.doi.org/10.26508/lsa.201800084