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Molecular analysis of human Ero1 reveals novel regulatory mechanisms for oxidative protein folding

Oxidative protein folding in the ER is driven mainly by oxidases of the endoplasmic reticulum oxidoreductin 1 (Ero1) family. Their action is regulated to avoid cell stress, including hyperoxidation. Previously published regulatory mechanisms are based on the rearrangement of active site and regulato...

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Detalles Bibliográficos
Autores principales: Moilanen, Antti, Korhonen, Kati, Saaranen, Mirva J, Ruddock, Lloyd W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238587/
https://www.ncbi.nlm.nih.gov/pubmed/30456358
http://dx.doi.org/10.26508/lsa.201800090