Cargando…

The histone chaperone FACT modulates nucleosome structure by tethering its components

Human FAcilitates Chromatin Transcription (hFACT) is a conserved histone chaperone that was originally described as a transcription elongation factor with potential nucleosome assembly functions. Here, we show that FACT has moderate tetrasome assembly activity but facilitates H2A–H2B deposition to f...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Tao, Liu, Yang, Edwards, Garrett, Krzizike, Daniel, Scherman, Hataichanok, Luger, Karolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238592/
https://www.ncbi.nlm.nih.gov/pubmed/30456370
http://dx.doi.org/10.26508/lsa.201800107