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Distinctive features of lincRNA gene expression suggest widespread RNA-independent functions

Eukaryotic genomes produce RNAs lacking protein-coding potential, with enigmatic roles. We integrated three approaches to study large intervening noncoding RNA (lincRNA) gene functions. First, we profiled mouse embryonic stem cells and neural precursor cells at single-cell resolution, revealing linc...

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Detalles Bibliográficos
Autores principales: Tuck, Alex C, Natarajan, Kedar Nath, Rice, Greggory M, Borawski, Jason, Mohn, Fabio, Rankova, Aneliya, Flemr, Matyas, Wenger, Alice, Nutiu, Razvan, Teichmann, Sarah, Bühler, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238598/
https://www.ncbi.nlm.nih.gov/pubmed/30456373
http://dx.doi.org/10.26508/lsa.201800124