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CARM1 methylates MED12 to regulate its RNA-binding ability

The coactivator-associated arginine methyltransferase (CARM1) functions as a regulator of transcription by methylating a diverse array of substrates. To broaden our understanding of CARM1's mechanistic actions, we sought to identify additional substrates for this enzyme. To do this, we generate...

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Detalles Bibliográficos
Autores principales: Cheng, Donghang, Vemulapalli, Vidyasiri, Lu, Yue, Shen, Jianjun, Aoyagi, Sayura, Fry, Christopher J, Yang, Yanzhong, Foulds, Charles E, Stossi, Fabio, Treviño, Lindsey S, Mancini, Michael A, O'Malley, Bert W, Walker, Cheryl L, Boyer, Thomas G, Bedford, Mark T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238599/
https://www.ncbi.nlm.nih.gov/pubmed/30456381
http://dx.doi.org/10.26508/lsa.201800117