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Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1
The Fanconi anemia pathway for DNA interstrand crosslink repair and the translesion synthesis pathway for DNA damage tolerance both require cycles of monoubiquitination and deubiquitination. The ubiquitin-specific protease-1 (USP1), in complex with USP1-associated factor 1, regulates multiple DNA re...
Autores principales: | Arkinson, Connor, Chaugule, Viduth K, Toth, Rachel, Walden, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238601/ https://www.ncbi.nlm.nih.gov/pubmed/30456385 http://dx.doi.org/10.26508/lsa.201800162 |
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