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Neuronal Aβ42 is enriched in small vesicles at the presynaptic side of synapses

The amyloid β-peptide (Aβ) is a physiological ubiquitously expressed peptide suggested to be involved in synaptic function, long-term potentiation, and memory function. The 42 amino acid-long variant (Aβ42) forms neurotoxic oligomers and amyloid plaques and plays a key role in the loss of synapses a...

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Detalles Bibliográficos
Autores principales: Yu, Yang, Jans, Daniel C, Winblad, Bengt, Tjernberg, Lars O, Schedin-Weiss, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238618/
https://www.ncbi.nlm.nih.gov/pubmed/30456353
http://dx.doi.org/10.26508/lsa.201800028