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Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1
Telomeres play crucial roles during tumorigenesis, inducing cellular senescence upon telomere shortening and extensive chromosome instability during telomere crisis. However, it has not been investigated if and how cellular transformation and oncogenic stress alter telomeric chromatin composition an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238619/ https://www.ncbi.nlm.nih.gov/pubmed/30456372 http://dx.doi.org/10.26508/lsa.201800121 |