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Transformation-induced stress at telomeres is counteracted through changes in the telomeric proteome including SAMHD1

Telomeres play crucial roles during tumorigenesis, inducing cellular senescence upon telomere shortening and extensive chromosome instability during telomere crisis. However, it has not been investigated if and how cellular transformation and oncogenic stress alter telomeric chromatin composition an...

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Detalles Bibliográficos
Autores principales: Majerska, Jana, Feretzaki, Marianna, Glousker, Galina, Lingner, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238619/
https://www.ncbi.nlm.nih.gov/pubmed/30456372
http://dx.doi.org/10.26508/lsa.201800121