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Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord

Locomotion is coordinated by neuronal circuits of the spinal cord. Recently, dI6 neurons were shown to participate in the control of locomotion. A subpopulation of dI6 neurons expresses the Wilms tumor suppressor gene Wt1. However, the function of Wt1 in these cells is not understood. Here, we aimed...

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Detalles Bibliográficos
Autores principales: Schnerwitzki, Danny, Perry, Sharn, Ivanova, Anna, Caixeta, Fabio V, Cramer, Paul, Günther, Sven, Weber, Kathrin, Tafreshiha, Atieh, Becker, Lore, Vargas Panesso, Ingrid L, Klopstock, Thomas, Hrabe de Angelis, Martin, Schmidt, Manuela, Kullander, Klas, Englert, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238623/
https://www.ncbi.nlm.nih.gov/pubmed/30456369
http://dx.doi.org/10.26508/lsa.201800106