Enzyme-free synthesis of cyclic single-stranded DNA constructs containing a single triazole, amide or phosphoramidate backbone linkage and their use as templates for rolling circle amplification and nanoflower formation

Cyclic oligonucleotides are valuable targets with a broad range of potential applications spanning molecular biology and nanotechnology. Of particular importance is their role as templates in the rolling circle amplification (RCA) reaction. We describe three different chemical cyclisation methods fo...

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Detalles Bibliográficos
Autores principales: Chen, Jinfeng, Baker, Ysobel R., Brown, Asha, El-Sagheer, Afaf H., Brown, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238721/
https://www.ncbi.nlm.nih.gov/pubmed/30542561
http://dx.doi.org/10.1039/c8sc02952k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238721/
https://www.ncbi.nlm.nih.gov/pubmed/30542561
http://dx.doi.org/10.1039/c8sc02952k

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