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Sub-zero temperature mechanically stable low molecular weight hydrogels

We show here a low molecular weight hydrogelator based on a functionalised-dipeptide which is stable down to temperatures of –12 °C despite being made from >99% water. This stabilty at low temperature can be extended to ∼–40 °C by gelling water : glycerol mixtures. The temperature range is wider...

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Detalles Bibliográficos
Autores principales: Fayter, Alice E. R., Gibson, Matthew I., Draper, Emily R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238726/
https://www.ncbi.nlm.nih.gov/pubmed/30555698
http://dx.doi.org/10.1039/c8tb01668b
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author Fayter, Alice E. R.
Gibson, Matthew I.
Draper, Emily R.
author_facet Fayter, Alice E. R.
Gibson, Matthew I.
Draper, Emily R.
author_sort Fayter, Alice E. R.
collection PubMed
description We show here a low molecular weight hydrogelator based on a functionalised-dipeptide which is stable down to temperatures of –12 °C despite being made from >99% water. This stabilty at low temperature can be extended to ∼–40 °C by gelling water : glycerol mixtures. The temperature range is wider than that of the glycerol : water mixtures alone. The rheological properties of the gels do not change at this low temperature compared to that of gels at 25 °C. This freezing point depression offers a potentially new method of transporting gels and offers the prospect of hydrogels being used at much lower working temperatures whilst retaining the desired rheological properties, this is useful for cryopreservation.
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spelling pubmed-62387262018-12-12 Sub-zero temperature mechanically stable low molecular weight hydrogels Fayter, Alice E. R. Gibson, Matthew I. Draper, Emily R. J Mater Chem B Chemistry We show here a low molecular weight hydrogelator based on a functionalised-dipeptide which is stable down to temperatures of –12 °C despite being made from >99% water. This stabilty at low temperature can be extended to ∼–40 °C by gelling water : glycerol mixtures. The temperature range is wider than that of the glycerol : water mixtures alone. The rheological properties of the gels do not change at this low temperature compared to that of gels at 25 °C. This freezing point depression offers a potentially new method of transporting gels and offers the prospect of hydrogels being used at much lower working temperatures whilst retaining the desired rheological properties, this is useful for cryopreservation. Royal Society of Chemistry 2018-11-28 2018-08-02 /pmc/articles/PMC6238726/ /pubmed/30555698 http://dx.doi.org/10.1039/c8tb01668b Text en This journal is © The Royal Society of Chemistry 2018 http://creativecommons.org/licenses/by/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0)
spellingShingle Chemistry
Fayter, Alice E. R.
Gibson, Matthew I.
Draper, Emily R.
Sub-zero temperature mechanically stable low molecular weight hydrogels
title Sub-zero temperature mechanically stable low molecular weight hydrogels
title_full Sub-zero temperature mechanically stable low molecular weight hydrogels
title_fullStr Sub-zero temperature mechanically stable low molecular weight hydrogels
title_full_unstemmed Sub-zero temperature mechanically stable low molecular weight hydrogels
title_short Sub-zero temperature mechanically stable low molecular weight hydrogels
title_sort sub-zero temperature mechanically stable low molecular weight hydrogels
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238726/
https://www.ncbi.nlm.nih.gov/pubmed/30555698
http://dx.doi.org/10.1039/c8tb01668b
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