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Sub-zero temperature mechanically stable low molecular weight hydrogels
We show here a low molecular weight hydrogelator based on a functionalised-dipeptide which is stable down to temperatures of –12 °C despite being made from >99% water. This stabilty at low temperature can be extended to ∼–40 °C by gelling water : glycerol mixtures. The temperature range is wider...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238726/ https://www.ncbi.nlm.nih.gov/pubmed/30555698 http://dx.doi.org/10.1039/c8tb01668b |
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author | Fayter, Alice E. R. Gibson, Matthew I. Draper, Emily R. |
author_facet | Fayter, Alice E. R. Gibson, Matthew I. Draper, Emily R. |
author_sort | Fayter, Alice E. R. |
collection | PubMed |
description | We show here a low molecular weight hydrogelator based on a functionalised-dipeptide which is stable down to temperatures of –12 °C despite being made from >99% water. This stabilty at low temperature can be extended to ∼–40 °C by gelling water : glycerol mixtures. The temperature range is wider than that of the glycerol : water mixtures alone. The rheological properties of the gels do not change at this low temperature compared to that of gels at 25 °C. This freezing point depression offers a potentially new method of transporting gels and offers the prospect of hydrogels being used at much lower working temperatures whilst retaining the desired rheological properties, this is useful for cryopreservation. |
format | Online Article Text |
id | pubmed-6238726 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-62387262018-12-12 Sub-zero temperature mechanically stable low molecular weight hydrogels Fayter, Alice E. R. Gibson, Matthew I. Draper, Emily R. J Mater Chem B Chemistry We show here a low molecular weight hydrogelator based on a functionalised-dipeptide which is stable down to temperatures of –12 °C despite being made from >99% water. This stabilty at low temperature can be extended to ∼–40 °C by gelling water : glycerol mixtures. The temperature range is wider than that of the glycerol : water mixtures alone. The rheological properties of the gels do not change at this low temperature compared to that of gels at 25 °C. This freezing point depression offers a potentially new method of transporting gels and offers the prospect of hydrogels being used at much lower working temperatures whilst retaining the desired rheological properties, this is useful for cryopreservation. Royal Society of Chemistry 2018-11-28 2018-08-02 /pmc/articles/PMC6238726/ /pubmed/30555698 http://dx.doi.org/10.1039/c8tb01668b Text en This journal is © The Royal Society of Chemistry 2018 http://creativecommons.org/licenses/by/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (CC BY 3.0) |
spellingShingle | Chemistry Fayter, Alice E. R. Gibson, Matthew I. Draper, Emily R. Sub-zero temperature mechanically stable low molecular weight hydrogels |
title | Sub-zero temperature mechanically stable low molecular weight hydrogels
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title_full | Sub-zero temperature mechanically stable low molecular weight hydrogels
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title_fullStr | Sub-zero temperature mechanically stable low molecular weight hydrogels
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title_full_unstemmed | Sub-zero temperature mechanically stable low molecular weight hydrogels
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title_short | Sub-zero temperature mechanically stable low molecular weight hydrogels
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title_sort | sub-zero temperature mechanically stable low molecular weight hydrogels |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238726/ https://www.ncbi.nlm.nih.gov/pubmed/30555698 http://dx.doi.org/10.1039/c8tb01668b |
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