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Knockdown of HOXA transcript at the distal tip suppresses the growth and invasion and induces apoptosis of oral tongue squamous carcinoma cells

BACKGROUND: Oral tongue squamous cell carcinoma (OTSCC) is an aggressive cancer which has high mortality rates. HOXA transcript at the distal tip (HOTTIP) is a lncRNA that can be used as a prognostic marker in multiple carcinomas. The expression of HOTTIP is found to be elevated in OTSCC tissues, an...

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Detalles Bibliográficos
Autores principales: Mu, Mingkui, Li, Yue, Zhan, Yuanbo, Li, Xin, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239101/
https://www.ncbi.nlm.nih.gov/pubmed/30519045
http://dx.doi.org/10.2147/OTT.S174637