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Emergence of tigecycline resistance in Escherichia coli co-producing MCR-1 and NDM-5 during tigecycline salvage treatment
OBJECTIVE: Here, we report a case of severe infection caused by Escherichia coli that harbored mcr-1, bla (NDM-5), and acquired resistance to tigecycline during tigecycline salvage therapy. METHODS: Antimicrobial susceptibility testing, Southern blot hybridization, and complete genome sequence of th...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239116/ https://www.ncbi.nlm.nih.gov/pubmed/30519062 http://dx.doi.org/10.2147/IDR.S179618 |