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Challenges and approaches to predicting RNA with multiple functional structures
The revolution in sequencing technology demands new tools to interpret the genetic code. As in vivo transcriptome-wide chemical probing techniques advance, new challenges emerge in the RNA folding problem. The emphasis on one sequence folding into a single minimum free energy structure is fading as...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Cold Spring Harbor Laboratory Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239171/ https://www.ncbi.nlm.nih.gov/pubmed/30143552 http://dx.doi.org/10.1261/rna.067827.118 |