Early developmental arrest and impaired gastrointestinal homeostasis in U12-dependent splicing-defective Rnpc3-deficient mice

Splicing is an essential step in eukaryotic gene expression. While the majority of introns is excised by the U2-dependent, or major class, spliceosome, the appropriate expression of a very small subset of genes depends on U12-dependent, or minor class, splicing. The U11/U12 65K protein (hereafter 65...

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Detalles Bibliográficos
Autores principales: Doggett, Karen, Williams, Ben B., Markmiller, Sebastian, Geng, Fan-Suo, Coates, Janine, Mieruszynski, Stephen, Ernst, Matthias, Thomas, Tim, Heath, Joan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239176/
https://www.ncbi.nlm.nih.gov/pubmed/30254136
http://dx.doi.org/10.1261/rna.068221.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239176/
https://www.ncbi.nlm.nih.gov/pubmed/30254136
http://dx.doi.org/10.1261/rna.068221.118

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