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Gene regulation by a glycine riboswitch singlet uses a finely tuned energetic landscape for helical switching

Riboswitches contain structured aptamer domains that, upon ligand binding, facilitate helical switching in their downstream expression platforms to alter gene expression. To fully dissect how riboswitches function requires a better understanding of the energetic landscape for helical switching. Here...

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Detalles Bibliográficos
Autores principales: Torgerson, Chad D., Hiller, David A., Stav, Shira, Strobel, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239177/
https://www.ncbi.nlm.nih.gov/pubmed/30237163
http://dx.doi.org/10.1261/rna.067884.118