The binding of Class II sRNA MgrR to two different sites on matchmaker protein Hfq enables efficient competition for Hfq and annealing to regulated mRNAs

MgrR is an Hfq-dependent sRNA, whose transcription is controlled by the level of Mg(2+) ions in Escherichia coli. MgrR belongs to Class II sRNAs because its stability in the cell is affected by mutations in Hfq differently than canonical, Class I sRNAs. Here, we examined the effect of mutations in R...

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Detalles Bibliográficos
Autores principales: Kwiatkowska, Joanna, Wroblewska, Zuzanna, Johnson, Kenneth A., Olejniczak, Mikolaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239178/
https://www.ncbi.nlm.nih.gov/pubmed/30217864
http://dx.doi.org/10.1261/rna.067777.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239178/
https://www.ncbi.nlm.nih.gov/pubmed/30217864
http://dx.doi.org/10.1261/rna.067777.118

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