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The binding of Class II sRNA MgrR to two different sites on matchmaker protein Hfq enables efficient competition for Hfq and annealing to regulated mRNAs
MgrR is an Hfq-dependent sRNA, whose transcription is controlled by the level of Mg(2+) ions in Escherichia coli. MgrR belongs to Class II sRNAs because its stability in the cell is affected by mutations in Hfq differently than canonical, Class I sRNAs. Here, we examined the effect of mutations in R...
Autores principales: | Kwiatkowska, Joanna, Wroblewska, Zuzanna, Johnson, Kenneth A., Olejniczak, Mikolaj |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239178/ https://www.ncbi.nlm.nih.gov/pubmed/30217864 http://dx.doi.org/10.1261/rna.067777.118 |
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