Acidic pH promotes nucleus pulposus cell senescence through activating the p38 MAPK pathway

Background: Nucleus pulposus (NP) cell senescence is an important cellular feature within the degenerative disc. It is known that a very acidic niche exists in the degenerative disc, which participates in regulating disc cell viability and matrix metabolism. Objective: The present study was aimed to...

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Detalles Bibliográficos
Autores principales: Fu, Jiabin, Yu, Wei, Jiang, Dianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239263/
https://www.ncbi.nlm.nih.gov/pubmed/30291218
http://dx.doi.org/10.1042/BSR20181451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239263/
https://www.ncbi.nlm.nih.gov/pubmed/30291218
http://dx.doi.org/10.1042/BSR20181451

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