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Decreased expression of circulating Aire and increased Tfh/Tfr cells in myasthenia gravis patients

Myasthenia gravis (MG) is a rare prototypical autoimmune disorder caused by antibodies (Ab) against postsynaptic membrane proteins. Most reports have investigated the role of autoimmune regulator gene (Aire) in thymic tissue in machianism of MG initiation. So far, the expression of Aire in human per...

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Detalles Bibliográficos
Autores principales: Zhao, Sijia, Ding, Jiaqi, Wang, Shengyuan, Li, Chuan, Guo, Peng, Zhang, Min, Li, Zhuyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239276/
https://www.ncbi.nlm.nih.gov/pubmed/29773681
http://dx.doi.org/10.1042/BSR20180096