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Mutational monitoring of EGFR T790M in cfDNA for clinical outcome prediction in EGFR-mutant lung adenocarcinoma

Several ultra-sensitive methods for T790M in plasma cell-free DNA (cfDNA) have been developed for lung cancer. The correlation between mutation-allele frequency (MAF) cut-off, drug responsiveness, and outcome prediction is an unmet needs and not fully addressed. An innovative combination of peptide...

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Detalles Bibliográficos
Autores principales: Su, Kang-Yi, Tseng, Jeng-Sen, Liao, Keng-Mao, Yang, Tsung-Ying, Chen, Kun-Chieh, Hsu, Kuo-Hsuan, Yang, Pan-Chyr, Yu, Sung-Liang, Chang, Gee-Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239293/
https://www.ncbi.nlm.nih.gov/pubmed/30444875
http://dx.doi.org/10.1371/journal.pone.0207001