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C. elegans ZHP-4 is required at multiple distinct steps in the formation of crossovers and their transition to segregation competent chiasmata

Correct segregation of meiotic chromosomes depends on DNA crossovers (COs) between homologs that culminate into visible physical linkages called chiasmata. COs emerge from a larger population of joint molecules (JM), the remainder of which are repaired as noncrossovers (NCOs) to restore genomic inte...

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Detalles Bibliográficos
Autores principales: Nguyen, Hanh, Labella, Sara, Silva, Nicola, Jantsch, Verena, Zetka, Monique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239344/
https://www.ncbi.nlm.nih.gov/pubmed/30379819
http://dx.doi.org/10.1371/journal.pgen.1007776