Small molecules that target group II introns are potent antifungal agents

Specific RNA structures control numerous metabolic processes that impact human health, and yet efforts to target RNA structures de-novo have been limited. In eukaryotes, the self-splicing group II intron is a mitochondrial RNA tertiary structure that is absent in vertebrates but essential for respir...

Descripción completa

Detalles Bibliográficos
Autores principales: Fedorova, Olga, Jagdmann, G. Erik, Adams, Rebecca L., Yuan, Lin, Van Zandt, Michael C., Pyle, Anna Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239893/
https://www.ncbi.nlm.nih.gov/pubmed/30323219
http://dx.doi.org/10.1038/s41589-018-0142-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239893/
https://www.ncbi.nlm.nih.gov/pubmed/30323219
http://dx.doi.org/10.1038/s41589-018-0142-0

Ejemplares similares