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Small molecules that target group II introns are potent antifungal agents

Specific RNA structures control numerous metabolic processes that impact human health, and yet efforts to target RNA structures de-novo have been limited. In eukaryotes, the self-splicing group II intron is a mitochondrial RNA tertiary structure that is absent in vertebrates but essential for respir...

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Detalles Bibliográficos
Autores principales:	Fedorova, Olga, Jagdmann, G. Erik, Adams, Rebecca L., Yuan, Lin, Van Zandt, Michael C., Pyle, Anna Marie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6239893/ https://www.ncbi.nlm.nih.gov/pubmed/30323219 http://dx.doi.org/10.1038/s41589-018-0142-0

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