The impact of combined gene mutations in inhA and ahpC genes on high levels of isoniazid resistance amongst katG non-315 in multidrug-resistant tuberculosis isolates from China

Whole-genome sequencing was used to analyze the profiles of isoniazid (INH) resistance-related mutations among 188 multidrug-resistant strains of Mycobacterium tuberculosis (MDR-TB) and mono-INH-resistant isolates collected in a recent Chinese national survey. Mutations were detected in 18 structura...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Liguo, Jiang, Fengting, Chen, Lihong, Zhao, Bing, Dong, Jie, Sun, Lilian, Zhu, Yafang, Liu, Bo, Zhou, Yang, Yang, Jian, Zhao, Yanlin, Jin, Qi, Zhang, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240042/
https://www.ncbi.nlm.nih.gov/pubmed/30446638
http://dx.doi.org/10.1038/s41426-018-0184-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240042/
https://www.ncbi.nlm.nih.gov/pubmed/30446638
http://dx.doi.org/10.1038/s41426-018-0184-0

Ejemplares similares