OCT3 promoter haplotype is associated with metformin pharmacokinetics in Koreans

Organic cation transporter 3 (OCT3) is expressed in various organs in humans and plays an important role in the transport of organic cations and drugs including metformin. In this study, we identified genetic variations of the OCT3 promoter and functionally characterized each variant by in vitro ass...

Descripción completa

Detalles Bibliográficos
Autores principales: Kwon, Eun Young, Chung, Jae-Yong, Park, Hyo Jin, Kim, Bo Min, Kim, Minsuk, Choi, Ji Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240047/
https://www.ncbi.nlm.nih.gov/pubmed/30446679
http://dx.doi.org/10.1038/s41598-018-35322-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240047/
https://www.ncbi.nlm.nih.gov/pubmed/30446679
http://dx.doi.org/10.1038/s41598-018-35322-6

Ejemplares similares