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Verbascoside: Identification, Quantification, and Potential Sensitization of Colorectal Cancer Cells to 5-FU by Targeting PI3K/AKT Pathway

Colorectal cancer (CRC) is the third most common cancer mortality worldwide. Although, 5-Fluorouracil (5-FU)-based chemotherapeutic regimens remain the mainstay for treatment of CRC, intrinsic and acquired resistance to 5-FU is the main reason for treatment failure and relapse. Adjunct or add-on the...

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Detalles Bibliográficos
Autores principales: Attia, Yasmeen M., El-Kersh, Dina M., Wagdy, Hebatallah A., Elmazar, Mohamed M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240071/
https://www.ncbi.nlm.nih.gov/pubmed/30446678
http://dx.doi.org/10.1038/s41598-018-35083-2