Genetic engineering a large animal model of human hypophosphatasia in sheep

The availability of tools to accurately replicate the clinical phenotype of rare human diseases is a key step toward improved understanding of disease progression and the development of more effective therapeutics. We successfully generated the first large animal model of a rare human bone disease,...

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Detalles Bibliográficos
Autores principales: Williams, Diarra K., Pinzón, Carlos, Huggins, Shannon, Pryor, Jane H., Falck, Alyssa, Herman, Forrest, Oldeschulte, James, Chavez, Michael B., Foster, Brian L., White, Sarah H., Westhusin, Mark E., Suva, Larry J., Long, Charles R., Gaddy, Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240114/
https://www.ncbi.nlm.nih.gov/pubmed/30446691
http://dx.doi.org/10.1038/s41598-018-35079-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240114/
https://www.ncbi.nlm.nih.gov/pubmed/30446691
http://dx.doi.org/10.1038/s41598-018-35079-y

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