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A majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation

Antiretroviral therapy (ART) suppresses viral replication in people living with HIV. Yet, infected cells persist for decades on ART and viremia returns if ART is stopped. Persistence has been attributed to viral replication in an ART sanctuary and long-lived and/or proliferating latently infected ce...

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Detalles Bibliográficos
Autores principales: Reeves, Daniel B., Duke, Elizabeth R., Wagner, Thor A., Palmer, Sarah E., Spivak, Adam M., Schiffer, Joshua T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240116/
https://www.ncbi.nlm.nih.gov/pubmed/30446650
http://dx.doi.org/10.1038/s41467-018-06843-5