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Mitotane (op’DDD) restores growth and puberty in nine children with Cushing’s disease

To investigate whether low-dose mitotane (up to 2 g/day) could be a temporary therapeutic alternative to transsphenoidal surgery (TSS) in pediatric Cushing’s disease (CD). Twenty-eight patients with CD aged 12.2 years (± 2.2) were referred to our center. We compared nine patients treated with mitota...

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Detalles Bibliográficos
Autores principales: Motte, Emmanuelle, Rothenbuhler, Anya, Gaillard, Stephan, Lahlou, Najiba, Teinturier, Cécile, Coutant, Régis, Linglart, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240149/
https://www.ncbi.nlm.nih.gov/pubmed/30352417
http://dx.doi.org/10.1530/EC-18-0215