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Sirtuin 3 deficiency aggravates contrast-induced acute kidney injury

BACKGROUND: Sirtuin 3 (Sirt3) is a key regulator of energy metabolism and oxidative stress. To investigate the role of Sirt3 in contrast-induced acute kidney injury (CIAKI), we established the model both in vivo and in vitro to explore the potential mechanisms. METHODS: In vivo, we established CIAKI...

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Detalles Bibliográficos
Autores principales: Zhang, Qinghai, Liu, Xun, li, Na, Zhang, Jihong, Yang, Jianmin, Bu, Peili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240230/
https://www.ncbi.nlm.nih.gov/pubmed/30445987
http://dx.doi.org/10.1186/s12967-018-1690-5