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RefCell: multi-dimensional analysis of image-based high-throughput screens based on ‘typical cells’

BACKGROUND: Image-based high-throughput screening (HTS) reveals a high level of heterogeneity in single cells and multiple cellular states may be observed within a single population. Currently available high-dimensional analysis methods are successful in characterizing cellular heterogeneity, but su...

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Detalles Bibliográficos
Autores principales: Shen, Yang, Kubben, Nard, Candia, Julián, Morozov, Alexandre V., Misteli, Tom, Losert, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240236/
https://www.ncbi.nlm.nih.gov/pubmed/30445906
http://dx.doi.org/10.1186/s12859-018-2454-1