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The role of neoantigen in immune checkpoint blockade therapy

Immune checkpoint inhibitor induces tumor rejection by activated host immune system. The anti-tumor immune response consists of capture, presentation, recognition of neoantigen, as well as subsequent killing of tumor cell. Due to the interdependence among this series of stepwise events, neoantigen p...

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Detalles Bibliográficos
Autores principales: Yi, Ming, Qin, Shuang, Zhao, Weiheng, Yu, Shengnan, Chu, Qian, Wu, Kongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240277/
https://www.ncbi.nlm.nih.gov/pubmed/30473928
http://dx.doi.org/10.1186/s40164-018-0120-y