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A tight balance of Karyopherin β1 expression is required in cervical cancer cells

BACKGROUND: Karyopherin β1 (Kpnβ1) is the main nuclear import protein involved in the transport of cargoes from the cytoplasm into the cell nucleus. Previous research has found Kpnβ1 to be significantly overexpressed in cervical cancer and other cancer tissues, and further studies showed that inhibi...

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Detalles Bibliográficos
Autores principales: Carden, Sarah, van der Watt, Pauline, Chi, Alicia, Ajayi-Smith, Aderonke, Hadley, Katie, Leaner, Virna D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240311/
https://www.ncbi.nlm.nih.gov/pubmed/30445944
http://dx.doi.org/10.1186/s12885-018-5044-8