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Plk1 regulates spindle orientation by phosphorylating NuMA in human cells

Proper orientation of the mitotic spindle defines the correct division plane and is essential for accurate cell division and development. In metazoans, an evolutionarily conserved complex comprising of NuMA/LGN/Gαi regulates proper orientation of the mitotic spindle by orchestrating cortical dynein...

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Detalles Bibliográficos
Autores principales: Sana, Shrividya, Keshri, Riya, Rajeevan, Ashwathi, Kapoor, Sukriti, Kotak, Sachin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240335/
https://www.ncbi.nlm.nih.gov/pubmed/30456393
http://dx.doi.org/10.26508/lsa.201800223