The inhibition of checkpoint activation by telomeres does not involve exclusion of dimethylation of histone H4 lysine 20 (H4K20me2)

DNA double-strand breaks (DSBs) activate the DNA damage checkpoint machinery to pause or halt the cell cycle.  Telomeres, the specific DNA-protein complexes at linear eukaryotic chromosome ends, are capped DSBs that do not activate DNA damage checkpoints.  This “checkpoint privileged” status of telo...

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Detalles Bibliográficos
Autores principales: Audry, Julien, Wang, Jinyu, Eisenstatt, Jessica R., Berkner, Kathleen L., Runge, Kurt W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240467/
https://www.ncbi.nlm.nih.gov/pubmed/30498568
http://dx.doi.org/10.12688/f1000research.15166.2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240467/
https://www.ncbi.nlm.nih.gov/pubmed/30498568
http://dx.doi.org/10.12688/f1000research.15166.2

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