In vitro and in vivo Effects of Lactate on Metabolism and Cytokine Production of Human Primary PBMCs and Monocytes

Lactate, the end product of anaerobic glycolysis, is produced in high amounts by innate immune cells during inflammatory activation. Although immunomodulating effects of lactate have been reported, evidence from human studies is scarce. Here we show that expression of genes involved in lactate metab...

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Detalles Bibliográficos
Autores principales: Ratter, Jacqueline M., Rooijackers, Hanne M. M., Hooiveld, Guido J., Hijmans, Anneke G. M., de Galan, Bastiaan E., Tack, Cees J., Stienstra, Rinke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240653/
https://www.ncbi.nlm.nih.gov/pubmed/30483253
http://dx.doi.org/10.3389/fimmu.2018.02564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240653/
https://www.ncbi.nlm.nih.gov/pubmed/30483253
http://dx.doi.org/10.3389/fimmu.2018.02564

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