Notch1 Inhibits Rosiglitazone-Induced Adipogenic Differentiation in Primary Thymic Stromal Cells

Adipocyte deposition is believed to be a primary characteristic of age-related thymic involution. Herein, we cultured primary thymic stromal cells (TSCs), used rosiglitazone, a potent peroxisome proliferator-activated receptor γ (PPARγ) agonist, to induce adipogenic differentiation, and investigated...

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Detalles Bibliográficos
Autores principales: Wang, Yajun, Tan, Jianxin, Du, Hongmei, Liu, Xue, Wang, Siliang, Wu, Simeng, Yuan, Zhe, Zhu, Xike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240707/
https://www.ncbi.nlm.nih.gov/pubmed/30483127
http://dx.doi.org/10.3389/fphar.2018.01284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240707/
https://www.ncbi.nlm.nih.gov/pubmed/30483127
http://dx.doi.org/10.3389/fphar.2018.01284

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