Tumour‐derived leukaemia inhibitory factor is a major driver of cancer cachexia and morbidity in C26 tumour‐bearing mice

BACKGROUND: Cancer cachexia is a metabolic wasting syndrome that is strongly associated with a poor prognosis. The initiating factors causing fat and muscle loss are largely unknown. Previously, we found that leukaemia inhibitory factor (LIF) secreted by C26 colon carcinoma cells was responsible for...

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Detalles Bibliográficos
Autores principales: Kandarian, Susan C., Nosacka, Rachel L., Delitto, Andrea E., Judge, Andrew R., Judge, Sarah M., Ganey, John D., Moreira, Jesse D., Jackman, Robert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240747/
https://www.ncbi.nlm.nih.gov/pubmed/30270531
http://dx.doi.org/10.1002/jcsm.12346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240747/
https://www.ncbi.nlm.nih.gov/pubmed/30270531
http://dx.doi.org/10.1002/jcsm.12346

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