Patient-Derived Induced Pluripotent Stem Cells and Organoids for Modeling Alpha Synuclein Propagation in Parkinson's Disease

Parkinson's disease (PD) is an age-associated, progressive neurodegenerative disorder characterized by motor impairment and in some cases cognitive decline. Central to the disease pathogenesis of PD is a small, presynaptic neuronal protein known as alpha synuclein (a-syn), which tends to accumu...

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Detalles Bibliográficos
Autores principales: Koh, Yong Hui, Tan, Li Yi, Ng, Shi-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240766/
https://www.ncbi.nlm.nih.gov/pubmed/30483063
http://dx.doi.org/10.3389/fncel.2018.00413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240766/
https://www.ncbi.nlm.nih.gov/pubmed/30483063
http://dx.doi.org/10.3389/fncel.2018.00413

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