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Novel inverse agonists for the orphan G protein-coupled receptor 6

The orphan G protein-coupled receptor 6 (GPR6) displays unique promise as a therapeutic target for the treatment of neuropsychiatric disorders due to its high expression in the striatopallidal neurons of the basal ganglia. GPR6, along with closely related orphan receptors GPR3 and GPR12, are phyloge...

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Detalles Bibliográficos
Autores principales: Laun, Alyssa S., Shrader, Sarah H., Song, Zhao-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240797/
https://www.ncbi.nlm.nih.gov/pubmed/30480157
http://dx.doi.org/10.1016/j.heliyon.2018.e00933