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IC-2 Suppresses Proliferation and Induces Apoptosis of Bladder Cancer Cells via the Wnt/β-Catenin Pathway

BACKGROUND: The Wnt/β-catenin signaling pathway participates in many important tumorigeneses processes, including bladder cancer. The inhibition of abnormal activation of Wnt pathways might provide a new approach to tumor treatment. In the present study, we investigated the role of IC-2, a novel Wnt...

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Detalles Bibliográficos
Autores principales: Wu, Lingfeng, He, Shunliang, He, Yi, Wang, Xueping, Lu, Linfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240849/
https://www.ncbi.nlm.nih.gov/pubmed/30415269
http://dx.doi.org/10.12659/MSM.910742