Silencing the FOLR2 Gene Inhibits Cell Proliferation and Increases Apoptosis in the NCI-H1650 Non-Small Cell Lung Cancer Cell Line via Inhibition of AKT/Mammalian Target of Rapamycin (mTOR)/Ribosomal Protein S6 Kinase 1 (S6K1) Signaling

BACKGROUND: The FOLR2 gene encodes folate receptor-beta (FR-beta), which is expressed by tumor-associated macrophages. The effects of FOLR2 gene expression in non-small cell lung cancer (NSCLC) remains unknown. This study aimed to investigate the effects of FOLR2 gene expression and gene silencing i...

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Detalles Bibliográficos
Autores principales: Xu, Xiaohua, Jiang, Jianyang, Yao, Lijuan, Ji, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240851/
https://www.ncbi.nlm.nih.gov/pubmed/30415267
http://dx.doi.org/10.12659/MSM.911384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240851/
https://www.ncbi.nlm.nih.gov/pubmed/30415267
http://dx.doi.org/10.12659/MSM.911384

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