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Allele-specific methylation of imprinted genes in fetal cord blood is influenced by cis-acting genetic variants and parental factors
AIM: To examine the effects of genetic variation, parental age and BMI on parental allele-specific methylation of imprinted genes in fetal cord blood samples. METHODOLOGY: We have developed SNP genotyping and deep bisulphite sequencing assays for six imprinted genes to determine parental allele-spec...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240887/ https://www.ncbi.nlm.nih.gov/pubmed/30238782 http://dx.doi.org/10.2217/epi-2018-0059 |