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Allele-specific methylation of imprinted genes in fetal cord blood is influenced by cis-acting genetic variants and parental factors

AIM: To examine the effects of genetic variation, parental age and BMI on parental allele-specific methylation of imprinted genes in fetal cord blood samples. METHODOLOGY: We have developed SNP genotyping and deep bisulphite sequencing assays for six imprinted genes to determine parental allele-spec...

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Detalles Bibliográficos
Autores principales: Potabattula, Ramya, Dittrich, Marcus, Böck, Julia, Haertle, Larissa, Müller, Tobias, Hahn, Thomas, Schorsch, Martin, Hajj, Nady El, Haaf, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240887/
https://www.ncbi.nlm.nih.gov/pubmed/30238782
http://dx.doi.org/10.2217/epi-2018-0059