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Nfia deletion in myeloid cells blocks expansion of myeloid-derived suppressor cells during sepsis

Sepsis-induced immunosuppression increases the risk of chronic infection and reduces survival. Myeloid-derived suppressor cells (MDSCs) expand in the bone marrow and spleen during murine polymicrobial sepsis, contributing to immunosuppression. A better understanding of molecular controls of MDSC pro...

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Detalles Bibliográficos
Autores principales: Dai, Jun, Kumbhare, Ajinkya, Williams, Danielle A, Youssef, Dima, Yao, Zhi Q, McCall, Charles E, Gazzar, Mohamed El
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240914/
https://www.ncbi.nlm.nih.gov/pubmed/29172874
http://dx.doi.org/10.1177/1753425917742956