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Nfia deletion in myeloid cells blocks expansion of myeloid-derived suppressor cells during sepsis
Sepsis-induced immunosuppression increases the risk of chronic infection and reduces survival. Myeloid-derived suppressor cells (MDSCs) expand in the bone marrow and spleen during murine polymicrobial sepsis, contributing to immunosuppression. A better understanding of molecular controls of MDSC pro...
Autores principales: | Dai, Jun, Kumbhare, Ajinkya, Williams, Danielle A, Youssef, Dima, Yao, Zhi Q, McCall, Charles E, Gazzar, Mohamed El |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240914/ https://www.ncbi.nlm.nih.gov/pubmed/29172874 http://dx.doi.org/10.1177/1753425917742956 |
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