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Exploring the contributions of two glutamate decarboxylase isozymes in Lactobacillus brevis to acid resistance and γ-aminobutyric acid production

BACKGROUND: The glutamate decarboxylase (GAD) system of Lactobacillus brevis involves two isoforms of GAD, GadA and GadB, which catalyze the conversion of L-glutamate to γ-aminobutyric acid (GABA) in a proton-consuming reaction contributing to intracellular pH homeostasis. However, direct experiment...

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Detalles Bibliográficos
Autores principales: Lyu, Changjiang, Zhao, Weirui, Peng, Chunlong, Hu, Sheng, Fang, Hui, Hua, Yujiao, Yao, Shanjing, Huang, Jun, Mei, Lehe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240960/
https://www.ncbi.nlm.nih.gov/pubmed/30454056
http://dx.doi.org/10.1186/s12934-018-1029-1